Gene description for CD63
Gene name CD63 molecule
Gene symbol CD63
Other names/aliases AD1
HOP-26
ME491
MLA1
OMA81H
Pltgp40
TSPAN30
Species Homo sapiens
 Experiment description of studies that identified CD63 in Cerebrospinal fluid

1
Experiment ID1712
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 6
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

2
Experiment ID1713
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 7
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

3
Experiment ID1714
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 8
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

4
Experiment ID1715
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 9
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

5
Experiment ID1716
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 10
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

6
Experiment ID1717
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 11
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

7
Experiment ID1718
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 12
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

8
Experiment ID1719
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 13
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

9
Experiment ID1720
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 14
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

10
Experiment ID1721
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 15
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

11
Experiment ID1722
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 16
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

12
Experiment ID1723
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 17
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

13
Experiment ID1736
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 1
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.012 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

14
Experiment ID1737
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 2
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.028 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

15
Experiment ID1738
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 3
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.045 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

16
Experiment ID1739
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 4
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.056 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

17
Experiment ID1740
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 5
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.065 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

18
Experiment ID1741
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 6
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.076 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

19
Experiment ID1742
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 7
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.097 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

20
Experiment ID1743
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 8
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.113 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

21
Experiment ID1744
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 9
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.138 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

22
Experiment ID1745
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 10
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.193 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

23
Experiment ID1746
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SampleCerebrospinal fluid
Sample nameFraction 11
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.219 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

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